When RVAD is connected "in serie" ("in parallel") mode, it takes blood from the right ventricle (atrium) and ejects it into the pulmonary artery. In the reported configuration the cardiocirculatory network is composed by: systemic arterial section modelled with two RLC (Ras1, Las1, Cas1 and Ras2, Las2 and Cas2) elements and a peripheral resistance Rcbs (see systemic network 2); pulmonary arterial section reproduced with 4-MW element (Rap, Rcbp, Lap and Cap); systemic venous section modelled with two variable resistaces (Rvs1 and Rvs2) and a compliance Cvs; pulmonary venous comparment implemented with 3-WM element (Rvp1, Rvp2 and Cvp). HEART: the ejection and contraction phases of both ventricles are reproduced using the variable elastance model; the right (left) atrium is described as a linear capacity characterised by constant value of compliance Cra (Cla) and unstressed volume, i.e. the contractile activity of the atrium is neglected (see the Numerical Heart Model (1) section). The connection of the ventricles to the circulatory network is realised by means of valves (mitral (MV), aortic (AV), tricuspid (TV) and pulmonary (PV)), which are assumed to be ideal.