CARDIOSIM©
  • Home
  • Heart Models 
    • Numerical Heart Model (1)
    • Numerical Heart Model (2)
  • Circulatory Models 
    • Systemic Circulation
    • Systemic Network 1
    • Systemic Network 2
    • Systemic Network 3
    • Systemic Network 4
    • Systemic Network 5
    • Systemic Network 6
    • Systemic Network 7
    • Pulmonary Circulation
    • Pulmonary Network 1
    • Pulmonary Network 2
    • Pulmonary Network 3
    • Pulmonary Network 4
    • Pulmonary Network 5
    • Pulmonary Network 6
    • Coronary Circulation
    • Coronary Network 1
    • Coronary Network 2
    • Coronary Network 3
    • Coronary Network 4
    • Coronary Network 5
    • Coronary Network 6
  • Circulatory Networks 
    • Left Circulatory Open Network
    • Right Circulatory Open Network
    • Full Circulatory Network
  • Assist Devices 
    • Pulsatile Flow Pump
    • Continuous Flow Pump
    • Intra-aortic balloon pump
    • Biventricular Pacemaker
    • Biventricular Assist Devices
    • Left Ventricular Assist Devices
    • Right Ventricular Assist Devices
    • Total Artificial Heart
    • Thoracic Artificial Lung
    • ECMO
    • TandemHeart
    • Impella
    • ProtekDuo
  • Experiments 
    • Patients
    • Patient 1
    • Patient 2
    • Animals
    • Animal 1
    • Animal 2
  • Statistical Analysis
  • Patents
  • Bibliography 
    • Books
    • Chapters in books
    • Papers
  • Thesis
  • Demos 
    • Demo 1
    • Demo 2
    • Demo 3
    • Demo 4
  • Login
CNR - Institute of Clinical Physiology - Secondary Section of Rome
Cardiovascular Numerical/Hybrid Modelling Lab: CARDIOSIM©
You are here: ...

Circulatory Models

Add new slide to this sequence
Re-order slides sequence

Coronary Network 1

1
Edit this slide

Coronary Network 1: Waterfall Model.

Downey and Kirk [1975] developed a coronary circulation model assuming that local blood flow in the myocardium is determined by waterfall mechanism. Panel [A] shows the collapsible-wall vessel surrounded by intramyocardial pressure (Pt). Panel [C] shows that coronary blood flow (CBF) is proportional to perfusion pressure (Pa) when Pt=0. Increasing Pt above zero, flow stops when Pt>Pa, since the higher pressure outside of the vessel causes it to collapse along its entire length. When Pt is between Pa and Pv, a partial collapse occurs at the point where pressure within the vessel falls below Pt. Panel (B) shows the electrical analogue of the waterfall model. It consists of a resistor in series with a diode and a battery. The diode-battery combination represents the intramyocardial pressure (the voltage Vt is equivalent to Pt, the voltage Va is equivalent to Pa). Two or more circuits presented in panel [B] can be assembled in parallel, each of them representing a layer of myocardium. The battery voltage is assumed to be proportional to left ventricular pressure (Plv), with a proportionality constant that decreases from lumen to epicardium taking negligible values there. According to Spaan [1981] the presented electrical circuit cannot describe all oscillatory pressure-flow relations observed experimentally. For instance, systolic arterial back-flow that occurs for low inflow pressures cannot be represented using the waterfall model.

In: MODELLING CARDIOVASCULAR SYSTEM AND MECHANICAL CIRCULATORY SUPPORT. Claudio De Lazzari Editor (2007). Published by Consiglio Nazionale delle Ricerche (CNR) ROMA. ISBN 978-88-8080-081-1.

Previous Next
  • Index of Circulatory Models
  • Systemic Circulation
  • Systemic Network 1
  • Systemic Network 2
  • Systemic Network 3
  • Systemic Network 4
  • Systemic Network 5
  • Systemic Network 6
  • Systemic Network 7
  • Pulmonary Circulation
  • Pulmonary Network 1
  • Pulmonary Network 2
  • Pulmonary Network 3
  • Pulmonary Network 4
  • Pulmonary Network 5
  • Pulmonary Network 6
  • Coronary Circulation
  • Coronary Network 1
  • Coronary Network 2
  • Coronary Network 3
  • Coronary Network 4
  • Coronary Network 5
  • Coronary Network 6
Back to top

SUPPORTED BY
SCIENTIFIC AGREEMENTS

Tested on  Google Chrome   Mozilla Firefox   Internet Explorer   Apple Safari

Best viewed at 1024x768 or greater

HTML 5 & CSS 3 |    

Copyright © 1991 - 2019 Claudio De Lazzari

Contacts

Cookie Policy  |  Legal trasparency

Web requirements

Sitemap

Credits