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CNR - Institute of Clinical Physiology - Secondary Section of Rome
Cardiovascular Numerical/Hybrid Modelling Lab: CARDIOSIM©
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Assist Device

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Impella

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Schematic representation of the cardiovascular system assembled with the Impella 2.5 pump. A detailed description of the cardiovascular network can be found in https://cardiosim.dsb.cnr.it/CirculatoryNetworks/fcn/fcn10

Impella 2.5 is a catheter-based mechanical device designed to offer circulatory support through percutaneous insertion. This pump is connected as left ventricular assist device (LVAD) across the aortic valve, generating blood flow in the ascending aorta with direct pressure and volume unloading.

In:  B. De Lazzari, M. Capoccia, R.Badagliacca, S. Bozkurt and C. De Lazzari. (2023). IABP Versus Impella Support in Cardiogenic Shock: “In Sili-co” Study.  J. Cardiovasc. Dev. Dis.  Mar 26, 10(4), 140. doi: 10.3390/jcdd10040140.

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Relationship between the flow through the Impella 2.5 pump and the pressure difference for different rotational speeds. The curves were obtained using the reported equation, with the values listed in Table

The curves in the figure are derived using the equation, and they are in good agreement with the experimental data collected during Impella 2.5 operation at pump speeds ranging from 25,000 to 51,000 rpm [Abiomed, Inc. Impella® Recover® LP 2.5 System-U Instruction for Use; Abiomed, Inc.: Danvers, MA, USA, 2006]

In:  B. De Lazzari, M. Capoccia, R.Badagliacca, S. Bozkurt and C. De Lazzari. (2023). IABP Versus Impella Support in Cardiogenic Shock: “In Sili-co” Study.  J. Cardiovasc. Dev. Dis.  Mar 26, 10(4), 140. doi: 10.3390/jcdd10040140.

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Values utilized in the equation to generate the curves shown in the preceding slide.

In:  B. De Lazzari, M. Capoccia, R.Badagliacca, S. Bozkurt and C. De Lazzari. (2023). IABP Versus Impella Support in Cardiogenic Shock: “In Sili-co” Study.  J. Cardiovasc. Dev. Dis.  Mar 26, 10(4), 140. doi: 10.3390/jcdd10040140.

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  • Index of Assist Devices
  • Pulsatile Flow Pump
  • Continuous Flow Pump
  • Intra-aortic balloon pump (IABP)
  • Biventricular Pacemaker (BiV)
  • Biventricular Assist Devices (BVAD)
  • Left Ventricular Assist Devices (LVAD)
  • Right Ventricular Assist Devices (RVAD)
  • Total Artificial Heart (TAH)
  • Thoracic Artificial Lung (TAL)
  • Extra-Corporeal Membrane Oxygenation (ECMO)
  • TandemHeart
  • Impella
  • ProtekDuo
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