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CNR - Institute of Clinical Physiology - Secondary Section of Rome
Cardiovascular Numerical/Hybrid Modelling Lab: CARDIOSIM©
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Heart Assist Devices

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Biventricular Assist Devices

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Electric Analogue of BVAD and Circulatory network. BVAD is Implemented Using  Pulsatile Pneumatic Flow Pump (left side) or the Continuous Flow Pump Hemopump (right side).

In CARDIOSIM© is possible to simulate the effects induced by Biventricular Assist Devices (BVADs) on haemodynamic/energetic variables of the cardiovascular system. It is possible to choose between LVAD and RVAD pneumatic pulsatile flow pumps (left side) and continuous flow pumps as Hemopump (right side).

In: MODELLING CARDIOVASCULAR SYSTEM AND MECHANICAL CIRCULATORY SUPPORT. Claudio De Lazzari Editor (2007). Published by Consiglio Nazionale delle Ricerche (CNR) ROMA. ISBN 978-88-8080-081-1.

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Electric Analogue of BVAD and Circulatory Network.

The pneumatic pulsatile flow pumps can be connected "in series" and/or "in parallel". When the pump is connecter "in series" ("in parallel") it takes blood from the ventricle (atrium) and ejects it into the aorta. Systemic (pulmonary) arterial sections is modelled using a modified windkessel with a systemic (pulmonary) arterial variable resistance Ras (Rap). Systemic (pulmonary) veous section is modelled with a variable resistance Rvs (simple resistance Rvp) and a compliance Cvs (Cvp). Pt is the mean intrathoracic pressure. In the electric analogue the behavior of the heart was implemented using the equations reported in the Numerical Heart Model (1) section.

In: MODELLING CARDIOVASCULAR SYSTEM AND MECHANICAL CIRCULATORY SUPPORT. Claudio De Lazzari Editor (2007). Published by Consiglio Nazionale delle Ricerche (CNR) ROMA. ISBN 978-88-8080-081-1.

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Electric Analogue of Biventricular Hemopump and Cardiovascular Network.

CARDIOSIM© library allow to assemble the cardiocirculatory network with biventricular Hemopump as shown in the slide. The network consists of the following sections: A] left and right heart; B] systemic arterial compartment; C] splanchnic and extrasplanchnic peripheral and venous circulation; D] peripheral and venous circulation in active muscle compartment; E] systemic thoracic veins; F] pulmonary arterial, peripheral and venous compartments; G] coronary circulation. Left (right) ventricular behaviour is described using a variable elastance model. A simple compliance is used in order to reproduce the behaviour of left (right) atrium. This representation permits to reproduce the only active phase of the atrium. In the electric analogue the behavior of the heart was implemented using the equations reported in the Numerical Heart Model (1) section. Equations used to solve the network are shown in "CVS & Hemopump: Equations" slides.

In: C. De Lazzari, M. Darowski, et al. (2006). Modelling in the study of interaction of Hemopump device and artificial ventilation. Computers in Biology and Medicine, 36 (11), 1235-1251.

In: MODELLING CARDIOVASCULAR SYSTEM AND MECHANICAL CIRCULATORY SUPPORT. Claudio De Lazzari Editor (2007). Published by Consiglio Nazionale delle Ricerche (CNR) ROMA. ISBN 978-88-8080-081-1.

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Previous Next
  • Index of Assist Devices
  • Pulsatile Flow Pump
  • Continuous Flow Pump
  • Intra-aortic balloon pump (IABP)
  • Biventricular Pacemaker (BiV)
  • Biventricular Assist Devices (BVAD)
  • Left Ventricular Assist Devices (LVAD)
  • Right Ventricular Assist Devices (RVAD)
  • Total Artificial Heart (TAH)
  • Thoracic Artificial Lung (TAL)
  • Extra-Corporeal Membrane Oxygenation (ECMO)
  • TandemHeart
  • Impella
  • ProtekDuo
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